Some users notice an impact within minutes while others say it takes days or weeks. This is because every individual has a unique combination of body weight, pain tolerance, diet, exercise and body chemistry. An additional factor is the overall health of a persons endocannabinoid system itself. Factors like poor diet, stress and environment are thought to deplete the ESC. Adding CBD with the benefit of omega 3 rich hempseed oil will work to rebuild the components of the ECS over time. Once this is complete, the ECS will become more and more effective in creating homeostasis throughout the body.